Acute lymphoblastic leukemia presenting as a breast lump: A report of two cases

Acute lymphoblastic leukemia presenting as a breast lump: A report of two cases

Blog Article

Extra-medullary leukemic infiltration of the breast by acute lymphoblastic leukemia (ALL) is very rare.We report two cases of ALL presenting as breast masses and diagnosed on fine-needle aspiration (FNA).Our first patient, a post-partum 30-year-old female, developed bilateral breast lumps in her last trimester of pregnancy and complained of easy fatigability.

Our second patient, Chaste Berry ( Vitex ) a 14-year-old girl, presented with a right-breast lump of 1-week duration.She had received treatment for ALL 1 year back and had been in complete remission for the last 1 year.FNA of the breast nodules done in both the cases revealed diffuse infiltration by lymphoblasts.

Subsequent hematological investigations confirmed bone marrow involvement by ALL in the first case and extra-medullary relapse in the second case.Fine-needle aspiration cytology (FNAC) is an easy and cost effective method for the early diagnosis of metastatic leukemic Flywheel Cover infiltration, avoiding unnecessary excisional biopsies in such cases.